Monday 13 June
8:30 – 12:00 Registration desk open
Session 1: Dysfunctional fat
Chair: Tiinamaija Tuomi
9:00 Opening words
Matti Rautalahti
Board member of Paulo Foundation
9:15 “Human genetic insights pertaining to the importance of adipocyte lipid droplets”
David Savage
Wellcome Trust Senior Clinical Fellow, Department of Clinical Biochemistry, University of Cambridge Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, UK
9:55 ”Novel genetic determinants of erythrocyte membrane fatty acid composition and metabolic phenotypes among Greenlandic Inuit”
Torben Hansen
Professor, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark
10:35 Coffee
11:05 “Mechanisms of liver fat accumulation in humans”
Hannele Yki-Järvinen
MD, FRCP Professor of Medicine, University of Helsinki, Finland
11:50 ”Molecular imaging of fatty acid metabolism in vivo”
Pirjo Nuutila
Professor, MD, PhD, Turku PET Centre, University of Turku / Hospital District of Southwest Finland
12:30 “HIF prolyl 4-hydroxylase-2 inhibition protects against development of metabolic syndrome and atherosclerosis”
Peppi Karppinen
University of Oulu, Finland
12:50 Lunch
13:50 Posters
Session 2: Functional interfaces of the endoplasmic reticulum with other cellular machineries
Functional interfaces of the endoplasmic reticulum with other cellular machineries
Chair: Vesa Olkkonen
15:00 EMBO YIP lecture: “Patrolling the borders: regulation of membrane function and identity by ubiquitin dependent proteolysis”
Pedro Carvalho
Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra, Barcelona, Spain
15:40 “Regulation of lipid storage by the actin cytoskeleton”
Elina Ikonen
PhD, MD, Academy Professor, University of Helsinki, Finland
16:20 “Dissecting autophagosome biogenesis using 3D imaging ”
Eeva-Liisa Eskelinen
University of Helsinki, Finland
16:40 Coffee
17:20 “Lipid metabolism-related vs. lipid droplet-related defects in hereditary axon degeneration”
Christian Beetz
PhD, Institut für Klinische Chemie und Laboratoriumsdiagnostik, Universitätsklinikum Jena, Germany
18:00 “The Importance of Phosphatidylethanolamine and Phosphatidylserine for Mitochondrial Function and Lenz-Majewski Syndrome”.
Jean Vance
PhD, FRSC, Professor, University of Alberta, Edmonton, Canada
19:00 Dinner and social programme
Tuesday 14 June
8:30 – 10:00 Registration desk open
Session 3: Lipid droplet biogenesis and interacting membrane systems
Chair:Elina Ikonen
9:00 TBA
Tobias Walther
Professor of Genetics and Complex Diseases, HSPH; Professor of Cell Biology, HMS; Associate Member, Broad Institute of MIT and Harvard; Investigator, Howard Hughes Medical Institute, US
9:40 “Molecular Simulations of Lipid Droplet Biogenesis”
Himanshu Khandelia
PhD, Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, DK
10:20 Coffee
10:50 “New insights into the formation and function of caveolae”
Rob Parton
Professor, Group Leader, Cell Biology and Molecular Medicine Division
Investigator, Centre for Rare Diseases Research
Investigator, Breakthrough Science Program in Mechanobiology
11:30 Posters
12:30 Lunch
13:30 Posters
Session 4: Mitochondrial dynamics and interactions
Chair: Elina Ikonen
14:10 “Cell-autonomous and non-autonomous consequences of mitochondrial dysfunction: the organelle and beyond”
Anu Wartiovaara
MD, PhD, Sigrid Jusélius Professor of Clinical Molecular Medicine, University of Helsinki, Finland
14:50 TBA
Luca Scorrano
M.D. and Ph.D, Professor of Biochemistry, University of Padova, Padova, Italy
15:30 “Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness”
Julia Döhla
University of Helsinki, Finland
15:50 Coffee
16:20 “The role of mitochondria in peroxisomal biogenesis”
Heidi McBride
Ph.D, Canada Research Chair in Mitochondrial Cell Biology; Killam Research Scholar; Professor, McGill University, Montreal Neurological Institute
17:00 “Mitochondrial quality control and intracellular vesicle traffic”
Howy Jacobs
Professor of Molecular Biology, Academy Professor, University of Tampere and Institute of Biotechnology, University of Helsinki, Finland
18:45 Conference dinner cruise
Wednesday 15 June
8:30 – 9:30 Registration desk open
Session 5: Lipolysis
Chair: Ville Paavilainen
9:00 ” Selective autophagy and intracellular lipid dynamics”
Ana Maria Cuervo
M.D., Ph.D., Professor, Albert Einstein College of Medicine, NY, US
9:40 “Intravascular and intracellular lipoprotein processing in brown adipose tissue”
Jörg Heeren
Professor, Institute for Biochemistry and Molecular Cell Biology, University Medical Center Hamburg‐Eppendorf, Germany
10:20 “Engaging adipose vasculature to burn fat”
Marius Robciuc
Wihuri Research Institute, University of Helsinki, Finland
10:40 Coffee
11:10 TBA
Rudolf Zechner
PhD, Professor of Biochemistry, Institute of Molecular Biosciences, University of
Graz
11:50 “A molecular switch that turns on selective autophagy”
Vlad Denic
Professor of Molecular and Cellular Biology, Harvard University, US
12:30 “Burning the fat: When Lipid Droplets meet Mitochondria”
Albert Pol
PhD, Group Leader, ICREA Professor, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Faculty of Medicine, University of Barcelona, Spain
13:10 Closing remarks