Theses

Doctoral school in health sciences thesis series, instructions for publication: Dissertationes Scholae Doctoralis Ad Sanitatem Investigandam Universitatis Helsinkiensis’.

tohtorinhattu

 

University of Helsinki: Helda, e-thesis database

 

 

2017

17/58) M. Sc. Pharm. Mónica Ferreira
Multifunctional Nanoparticles for Targeted Drug Delivery and Imaging for Ischemic Myocardial Injury
15.12.2017, Auditorium 2, Info Center Korona, Viikinkaari 11 A
Opponent: Prof. Christel Bergström, University of Uppsala

16/57) M.D. Kuan-Yin Tseng
Rejuvenating the brain’s endogenous regenerative potential: focus on the role of MANF in brain development and ischemic brain injury
15.12.2017, Biocenter 2, auditorium 1041, Viikinkaari 5
Opponent: Ass. Prof. Luo Yu, Case Western Reserve University, USA

15/56) M.Sc. Clin Pharm Niina Laine
Use of Antimicrobials in a Tertiary Children’s Hospital
8.12.2017, Yliopistonkatu 3, Porthania, Lecture hall PIII.
Opponent: Doc. Asko Järvinen, Univeristy of Helsinki

14/55) M.Sc. Tiina Lantto
Cytotoxic and apoptotic effects of selected phenolic compounds and extracts from edible plants
10.11.2017, Auditorium 2, Info Center Korona, Viikinkaari 11 A
Opponent: Ass. Prof. Urmas Arumäe, Tallinn University of Technology, Estonia

13/54) M.Sc. (Pharm) Jenni Pessi
“Insights into particle formation and analysis”
3.11.2017 Auditorium 2, Info Center Korona, Viikinkaari 11 A
Opponent: Prof. João Pinto, University of Lissabon

12/53) M.Sc. (Pharm) Miina Ruokolainen
“Imitation of biologically relevant oxidation reactions by titanium dioxide photocatalysis: Advances in understanding the mimicking of drug metabolism and the oxidation of phosphopeptides”.
27.10.2017, Biocenter 2, Auditorium 2041, Viikinkaari 5.
Opponent: Ass. Prof. Christian Janfelt, University of Copenhagen

11/52) M.Sc. Anna-Maija Penttinen
“GDNF and Neurturin isoforms in an experimental model of Parkinson’s disease”
23.9.2017 at 10:00 o’clock, Viikin infokeskus Korona, sali 2, Viikinkaari 11.
Opponent: Privat docent Liliane Tenenbaum, Lausanne University Hospital

10/51) Lic. Pharm. Eeva Suvikas-Peltonen
“Lääkkeiden turvallisen käyttökuntoon saattamisen edistäminen sairaaloiden osastoilla”.
23.9.2017, Satakunta Central Hospital, auditorium, Sairaalantie 3, Pori.
Opponent: Doc. Kari Wallenius, University of Eastern, Finland

9/50) M.Sc. (Pharm) Boriss Sagalajev
“Neuropathic pain: amygdaloid stress as culprit and cortical stimulation as treatment”
4.8.2017, Lecture hall 2, Biomedicum 1, Haartmaninkatu 8, Meilahti
Opponent: Prof. Rashid Giniatullin, University of Eastern, Finland

8/49) M.Sc. (Pharm) Sirpa Regina
“Pitääkö pohtia miksi joku käyttää?” Unettomuus ja sen hoito – Apteekkifarmaseuttien näkemyksiä, kokemuksia ja käytäntöjä”
15.6.2017, Infokeskus Korona, sali 235, Viikinkaari 11.
Opponent: Doc. Helena Liira, University of Helsinki

7/48) M.Sc. (Pharm) Noora Sjöstedt
“In vitro evaluation of the pharmacokinetic effects of BCRP interactions”
16.6.2017, Metsätieteiden talo, luentosali 106 (B5), Latokartanonkaari 7, Viikki
Opponent: Prof. Peter W. Swaan, University of Maryland, Baltimore

6/47 MD Katriina Tarkiainen
“Pharmacogenetics of Carboxylesterase 1”
9.6.2017, Biomedicum, lecture hall, Haartmaninkatu 8, Meilahti
Opponent:
Doc., Senior Medical Officer Miia Turpeinen, MD, PhD, University of Oulu and Oulu University Hospital

5/46 M.Sc. (Pharm) Reeta Talka
“Effects of Opioids on Neuronal Nicotinic Acetylcholine Receptors”
19.5.2017, Biocenter 2, Auditorium 2041, Viikinkaari 5.
Opponent: Prof. Neil Millar, University College London

4/45 M.Sc. Andreas Helfenstein
“Fighting Bugs by Numbers: Bioinformatics Tools for Antimicrobial Drug Discovery”
28.4.2017, Auditorium 2, Info Center Korona (Viikinkaari 11 A)
Opponent : Prof. chief information officer John Overington, Medicines Discovery Catapult, UK

3/44 M.Sc. (Pharm) Anna-Riia Holmström
“Learning from medication errors in health care – how to make
medication error reporting systems work?”
28.4.2017, University main building, Auditorium XIV, Fabianinkatu 33
Opponent: PharmD, PhD Kenneth Shermock, Johns Hopkins Hospital, Bloomberg School of Public Health, USA

2/43) M.Sc. (Pharm) Jaana Hautala
“Improving the Palatability of Minitablets for Feline Medication ”
31.3.2017, Biocenter 2, Auditorium 2041, Viikinkaari 5.
Opponent: Prof. Jörg Breitkreutz, Heinrich-Heine-University Düsseldorf

1/42) M.Sc Elisa Lázaro Ibáñez “Extracellular Vesicles: Prospects in Prostate Cancer Biomarker Discovery and Drug Delivery”
3.3.2017, Auditorium 2, Info Center Korona (Viikinkaari 11 A)
Opponent: Prof. Janusz Rak, McGill University, Montreal Children´s Hospital, Montreal

2016

12/41) M.Sc. Elina Karhu “Natural Products as a Source for Rational Antichlamydial Lead-Discovery”
9.12.2016, Auditorium 236, Info Center Korona (Viikinkaari 11 A)
Opponent: Prof. Anders Backlund, Uppsala Universitet

11/40) M.Sc. Maarit Dimitrow “Development and Validation of a Drug-related
Problem Risk Assessment Tool for Use by Practical Nurses Working
With Community-Dwelling Aged”
25.11.2016, University of Helsinki, Main building, Small lecture hall (4050), Fabianinkatu 33
Opponent: Doc., MD. PhD. Pirkko Jäntti, University of Tampere.

10/39)  M.Sc. (Pharm) Tatu Lajunen ”Liposomal drug delivery: light triggered drug release and targeting to the posterior segment of the eye”
14.10.2016, Infocenter Korona, Auditorium 1, Viikinkaari 11, University of Helsinki.
Opponent: Prof. Paolo Caliceti, University of Padova, Italy

9/38) M.Sc. Kristina Malinovskaja-Gomez ”Transdermal Iontophoresis – Delivery Control by Ion-Exchange Fibers and Nanocarriers”
7.10.2016, Auditorium 1, Info Center Korona (Viikinkaari 11 A), University of Helsinki.
Opponent: Prof. Yogeshvar. N Kalia, University of Geneva, Switzerland

8/37) M.Sc. (Pharm) Meri Kekäle “Chronic Myeloid Leukemia Patients’
Adherence to Tyrosine Kinase Inhibitors in Finland – A Journey of Eighty-six Patients”
26.8.2016, Biomedicum Helsinki, Auditorium 2.
Opponent: Professor Helvi Kyngäs, University of Oulu

7/36) M.Sc. Jaakko Kopra “Endogenous GDNF as a regulator of midbrain dopamine neurons”
12.8.2016, Viikki Biocenter 2, auditorium 1041, University of Helsinki
Opponent: Doc. Edgar Kramer, Institute of Applied Physiology, Ulm University

6/35) M.Sc. (Pharm) Sami Svanbäck “Toward accurate high-throughput
physicochemical profiling using image-based single-particle analysis”
15.7, Viikki Infocenter Korona, Auditorium 1, Viikinkaari 11, University of Helsinki.
Opponent

5/34) M.Sc. Barbara Herranz “Multi-Approach Design and Fabrication of Hybrid Composites for Drug Delivery and Cancer Therapy”
27.5.2016, Viikki campus
Opponent: Prof. Leigh Canham, School of Physics, University of Birmingham

4/33) M.Sc. (Pharm) Neha Shrestha “Mesoporous silicon systems for oral protein/peptide-based diabetes mellitus therapy”.
1.4.2016
Opponent: Ass. Prof. Alejandro Sosni, Technion – Israel Institute of Technology.

3/32) M.Sc. Mari Hirvinen “Immunological boosting and personalization of oncolytic virotherapies for cancer treatment”
1.4.2016 at noon, Biocentrum 2, auditorium 1041, Viikinkaari 5E
Opponent: Prof. Maria Croyle, University of Texas at Austin

2/31) M.D. Juho Heinonen “Intravenous lipid emulsion for treatment of local anaesthetic and tricyclic antidepressant toxicity”
19.3.2016 at 10 o’clock, University main building, Auditorium XIV.
Opponent: Universitetslektor, adjungerad Kai Knudsen, Sahlgrenska universitetssjukhuset, Göteborg

1/30) M.Sc. Sofia Montalvão “Screening of Marine Natural Products and Their Synthetic Derivatives for Antimicrobial and Antiproliferative Properties”
26.02.2016 at noon, Viikki Infocenter Korona, Auditorium 2, Viikinkaari 11, University of Helsinki.
Opponent: Prof. Maria Valeria D’Auria, University of Naples Federico II

2015

17/29) M.Sc. (Pharm) Karmen Kapp “Polyphenolic and essential oil composition of Mentha and their antimicrobial effect”
22.12.2015 at noon, Biocentrum 2, auditorium 1041, Viikinkaari 5E.
Opponent: Prof. Rudolf Bauer, University of Graz

16/28 M.Sc. (Pharm) Minna Matikainen “Launching New Products in the Finnish Pharmaceutical Industry: A Relationship Approach”
11.12.2015 at noon, Small Hall, University Main Building
Opponent: Adj. Prof. Paula Rytilä, University of Helsinki

15/27) M.Sc Raisa Haavikko “Synthesis of betulin derivatives with new bioactivities”
6.11.15 at noon, Biocentrum 2, auditorium 1041, Viikinkaari 5E, Viikki campus, University of Helsinki.
Opponent: Prof. Dulcie Mulholland, University of Surrey

14/26) M.Sc (Pharm) Mari Savolainen “The Effects of Prolyl Oligopeptidase Inhibition in α-Synuclein Based Mouse Models of Parkinson’s Disease“
30.10.2015 at noon, Biocentrum 2, auditorium 1041, Viikinkaari 5, University of Helsinki
Opponent: Prof. Heikki Tanila, University of Eastern Finland

13/25) M.Sc. (Pharm) Eva María del Amo Páez “Ocular and systemic pharmacokinetic models for drug discovery and development”
11.9.2015 at noon, Medistudia building, Yliopistonranta 1A, lecture hall MS301, Kuopio,
Opponent: Professor Olavi Pelkonen, University of Oulu

12/24) M.Sc. Polina Ilina “The role of the carrier and the endocytic pathway in non-viral gene delivery”
13.7.2015 at noon, Biocentrum 3, auditorium 2402, Viikinkaari 1, University of Helsinki
Opponent: Prof. Stefaan De Smedt, Ghent University, Belgium

11/23) M. Sc. (Pharm) Leena Keurulainen “Synthesis and evaluation of antichlamydial, antileishmanial and antimalarial activity of benzimidazole and benzoxadiazole derivatives”
26.6.2015 at noon Info Center Korona, auditorium 2 (Viikinkaari 11), University of Helsinki.
Opponent: Prof. Daniel Kikelj, University of Ljubljana

10/22) M. Sc. (Pharm) Annika Tuomela “Nanocrystals for Drug Delivery Applications”
16.6.2015 at noon, Infokeskus Korona, Sali 2, Viikinkaari 11.
Opponent: Prof. Guy Van den Mooter, University of Leuven

9/21) M. Sc. Susanna Nybond “Cell-based bioluminescent high-throughput screening methods in antibacterial drug discovery”
4.6.2015 at noon,Viikki Infocenter Korona, auditorium 2, Viikinkaari 11, University of Helsinki.
Opponent: Prof. Aldo Roda, University of Bologna

8/20) M. Sc. (Pharm) Kalle Aaltonen “Efficacy, Safety and Clinical Outcomes of Biologic Drugs in the Treatment of Rheumatoid Arthritis”
29.5.2015 at noon, auditorium 2, Info Center Korona (Viikinkaari 11A), University of Helsinki.
Opponent: Doc. Arja Helin-Salmivaara, University of Turku

7/19) M.Sc. (Pharm) Tina Suominen “Analysis of neurotransmitters, neurosteroids and their metabolites in biological samples”
22.5.2015 at noon on 22 May 2015 at 12:00. University main building, Auditorium XII, Fabianinkatu 33, University of Helsinki,
Opponent: Prof. Thomas Hankemeier, Leiden University

6/18) M.Sc. (Pharm) Ira Soppela “Modern analytical approaches to pharmaceutical powder characterisation and processing”
24.4.2015, at 12 noon, lecture room 2, B building, Latokartanonkaari 7, University of Helsinki.
Opponent: Prof. Thomas De Beer, Ghent University.

5/17) M.Sc. (pharm) Nina Nordman “Microchip technology in mass spectrometry-based bioanalysis: Advances in the analysis of peptides, proteins, and pharmaceuticals”
17.4.2015 at noon, Huvudbyggnaden, auditorium XIV, Unionsgatan 34, University of Helsinki.
Opponent: Prof. Elisabeth Verpoorte, University of Groningen

4/16) PhD Amna Shawesh “Indomethacin Topical Formulations Development And The Effect Of Compositions On The Physical Characteristics And Stability”
21.3. 2015 at noon, Auditorium 2, Viikki Infocenter, University of Helsinki
Opponent: Doc Pharmacist Pasi Merkku, University of Helsinki

3/15) M.Sc. (Chem) Chang-Fang Wang “Chemical surface modification of porous silicon nanoparticles for cancer therapy”.
2.3.2015 at noon, Auditorium 1, Infocenter, Viikinkaari 11, University of Helsinki
Opponent: Dr. Luca De Stefano, Unit of Naples-National Research Council, Italy

2/14) M. Sc. (Pharm) Mohammad-Ali Shahbazi “Effect of Surface Chemistry on the Immune Responses and Cellular Interactions of Porous Silicon Nanoparticles”
13.2.2015 at noon, Lecture Hall 2, B-building, Latokartanonkaari 7, Helsinki.
Opponent: Professor Ijeoma Uchegbu, University College of London

1/13) M. Sc. (Pharm) Milica Maksimovic “Behavioural and pharmacological characterization of a mouse model for psychotic disorders – focus on glutamatergic transmission”
16.1.2015 at 14 o’clock, Lecture Hall 2, Biomedicum Helsinki 1, Haartmaninkatu 8, University of Helsinki
Opponent: Doc. Eriika Savontaus, University of Turku

2014

12) MD. Tuomas Lilius “New insights into enhancing morphine analgesia: from glia to pharmacokinetics”
28.11.2014 at noon, Haartman-institute, lecture hall 2, Haartmaninkatu 3.
Opponent: Prof. Mika Scheinin, University of Turku

11) M.Sc. Jaana Palomäki “Immunotoxicological effects induced by engineered nanomaterials”
31.10.2014 at noon, Finnish Institute of Occupational Health, Lecture hall (3rd floor), Topeliuksenkatu 30, University of Helsinki
Opponent: Prof. Bengt Fadeel, Karolinska Institutet

10) M.Sc. (Pharm) Anne Filppula “Role of CYP2C8 in the metabolism of montelukast and imatinib – Studies in vitro, in silico and in humans”
14.11.2014 at noon, Biomedicum 1, föreläsningssal 3, Haartmansgatan 8, University of Helsinki.
Opponent: Professor Kim Brøsen, University of Southern Denmark

9) M.Sc. Linda Ahonen “Method development for the analysis of steroids, vitamin D and oxysterols”
3.10.2014 at noon, auditorium 2, Info Center Korona (Viikinkaari 11A), University of Helsinki
Opponent: Prof. Achille Cappiello, University of Urbino, Italy

8) M.Sc. Leena-Stiina Kontturi “Cell encapsulation in hydrogels for long-term protein delivery and tissue engineering applications”
6.9. 2014, at noon, Auditorium 2, Korona Information Centre, University of Helsinki
Opponent: Ph.D. Kristiina Järvinen, Keuruun apteekki (UEF)

7) M.Sc. (Pharm) Melina Malinen “Development of organotypic liver cell cultures in three-dimensional biomaterial hydrogels”
01.09.2014 at noon, Infocenter Korona, Lecture hall 1, Viikki, University of Helsinki
Opponent: Prof. Kim L. R. Brouwer, UNC Eshelman School of Pharmacy, USA

6) MD Juha Lempiäinen “Ischaemia-Reperfusion-Induced Kidney Injury Experimental studies on the effects of caloric restriction, AMPK activator AICAR and α2-adrenoceptor agonists in the rat”
29.8.2014 at 12 noon, Biomedicum Lecture hall, Meilahti, University of Helsinki
Opponent: Prof. Markku Koulu, MD, PhD, University of Turku

5) M.Sc. Dongfei Liu “Porous Silicon-Based Multicomposites for Controlled Drug Delivery”
29.8.2014 at 13.00 o’clock, Lecture Hall 2, Info Center Korona (Viikinkaari 11A), University of Helsinki
Opponent: Prof. Bruno Sarmento, Institute of Biomedical Engineering (INEB), University of Porto, Portugal

4) M.Sc. Aniket Magarkar “Molecular dynamics simulations of drug delivery liposomes and their interactions with bloodstream elements”
25.8.2014 at 11 o’clock, auditorium 1, Infocenter Korona, Viikinkaari 11, University of Helsinki
Opponent: Prof. Roland Faller, University of California, USA

3) M.Sc. Astrid Subrizi “Delivery of biologics to the retinal pigment epithelium”
22.8.2014 at 13 o’clock, Lecture hall 5 (A106), B building, Latokartanonkaari 7, Viikki, University of Helsinki.
Opponent: Prof. Jorgen Kjems, Aarhus University, Denmark

2) M.Sc. Kirsi Rosenqvist “The effect of systematically and locally administered clodronate on bone quality.”
23.5.2014 at noon, Latokartanonkaari 7, Building B, lecture hall 3, University of Helsinki
Opponent: Prof. Jukka Mönkkönen, University of Eastern Finland

1) M.Sc. (Pharm) Susanne Bäck “CDNF in an experimental model of Parkinson’s disease: studies on gene therapy and protein infusion”
7.2.2014 at noon, Viikki Biocenter, Auditorium 1041, University of Helsinki. Opponent: Dr. Barry Hoffer, Biomedical Research Center, National Institute of Drug Abuse, Baltimore, USA

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