PREP in neurodegenerative diseases -group got another publication on Neuroscience when Mirva Hannula’s manuscript “Prolyl oligopeptidase colocalizes with alpha-synuclein, beta-amyloid, tau protein and astroglia in the post-mortem brain samples with Parkinson’s and Alzheimer’s diseases” got accepted.

In this manuscript, we observed that PREP actually colocalizes with several hallmark proteins of neurodegenerative diseases, such as alpha-synuclein in Parkinson’s and beta-amyloid in Alzheimer’s. This further stresses the role of PREP in neurodegenerative diseases with protein modifications, and opens novel possibilities for further studies.

The manuscript abstract should be available soon online here.